Review · Frontiers in nutrition · 2023Conflicts declared

Vinegar research and sugarcane vinegar's health effects

What it found

Sugarcane vinegar lowered blood fats and body weight in mice fed a high-fat diet, and showed antioxidant effects in lab tests.

The paper also describes how vinegar is made and what compounds it contains.

What they found

Animal and lab studies

Blood fats in mice

In mice fed a high-fat diet, sugarcane vinegar significantly reduced total cholesterol, triglycerides, and LDL cholesterol, and raised HDL cholesterol. It also reduced blood sugar and fat accumulation.

Antioxidant effects

Sugarcane fruit wine and original sugarcane vinegar had strong scavenging effects on DPPH and OH in lab tests, and chelated metal ions. The effect increased with sample volume.

Body weight and organs

High-concentration sugarcane vinegar effectively reduced body weight in high-fat mice. Except for a significant increase in lung, other organs showed no significant difference.

Other findings

Compounds in vinegar

Sugarcane vinegar is rich in phenolic substances like vanillin, coumarin, chlorogenic acid, and caffeic acid. Its total phenolic content was higher than commercial apple cider vinegar beverages.

How vinegar is made

Vinegar is made by a two-step fermentation: yeasts turn sugars into alcohol, then acetic acid bacteria turn alcohol into acetic acid. Sugarcane vinegar uses sugarcane juice fermented with wine yeast and LB acetate bacteria.

Aroma and flavour

Vinegar's flavour comes from acetic acid and other compounds like organic acids, esters, ketones, and aldehydes. These are influenced by raw materials, microbes, and production process.

What the authors conclude

  • They say future research should focus on using multi-omics technologies to better understand how microbes produce volatile organic compounds in vinegar.
  • They note that it is highly challenging to explain the production processes of these compounds because they change during vinegar making.

How it was done

Health problems are closely linked to diet, and vinegar has long been used in traditional medicine. The authors wanted to map the current state of vinegar research and highlight areas for future study.

The authors reviewed existing studies on vinegar, including its production, chemistry, and health effects. They also used bibliometric analysis to visualise the knowledge map of vinegar research based on literature data.

What it can’t tell you

  • The health effects in this paper come mainly from animal and lab studies. They cannot show what happens in people.
  • The paper does not report human trials on sugarcane vinegar's effects on blood fats, weight, or antioxidants.
  • The review describes many compounds in vinegar but does not prove that any of them cause health benefits in people.

The paper

Title
Vinegar: A potential source of healthy and functional food with special reference to sugarcane vinegar
Type
ReviewThe authors read earlier studies and describe what they found. It isn’t a new study.
Evidence
Animals and lab studies
Summarised from
Full text
Licence
CC BY.
Cite
Chen GL, Zheng FJ, Lin B, et al (2023). Vinegar: A potential source of healthy and functional food with special reference to sugarcane vinegar. Frontiers in nutrition. doi:10.3389/fnut.2023.1145862Free full textPubMed 37006937DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error