Systematic review and meta-analysis · Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Abstract onlyConflicts declared

Chia seeds and heart, blood and waist measures

What it found

In people, chia supplementation was linked to small improvements in blood pressure, cholesterol, triglycerides, inflammation and waist size.

The authors rate the certainty of this evidence as moderate to low.

What they found

Studies in people

Blood pressure

Chia supplementation was linked to reductions in diastolic and systolic blood pressure in people.

Cholesterol and triglycerides

Total cholesterol, LDL cholesterol and triglycerides went down with chia in people. HDL cholesterol also went down slightly.

Waist size

Waist circumference was reduced with chia supplementation in people.

Inflammation

C-reactive protein, a marker of inflammation, was reduced with chia in people.

Other findings

Certainty of evidence

The authors graded the certainty of the evidence as moderate to low for most outcomes.

What the authors conclude

“Overall, chia supplementation may offer modest but statistically significant benefits for improving blood pressure, lipid profiles, inflammation, and central obesity.”
Al-Younis ZK, Al-Shawi SG, Kareem AK, et al, 2025

Also in their conclusions

  • They conclude that chia supplementation may offer modest but statistically significant benefits for improving blood pressure, lipid profiles, inflammation, and central obesity.
  • They note that the certainty of evidence ranged from moderate to low for most outcomes.

How it was done

Chia seeds have attracted interest for possible health benefits, but the authors say their overall effectiveness remains uncertain because high-quality evidence is limited and studies differ from each other.

They combined data from eight meta-analyses of randomised controlled trials, involving about 2,500 participants. The studies looked at blood pressure, blood fats, inflammation and body measurements.

What it can’t tell you

  • We summarised it from the abstract only.
  • The evidence comes from studies that followed people over time, so it can show links but not prove that chia causes these changes.
  • The authors rate the certainty of the evidence as moderate to low, so the true size of any effect may differ.

The paper

Title
A Critical Review of the Health Benefits Associated with Chia Seeds (Salvia Hispanica L.)
Type
Systematic review and meta-analysisThe authors follow a set, published method to find every relevant study, then combine the numbers from them into one result.
Evidence
Studies in people
Summarised from
Abstract only
Cite
Al-Younis ZK, Al-Shawi SG, Kareem AK, et al (2025). A Critical Review of the Health Benefits Associated with Chia Seeds (Salvia Hispanica L.). Plant foods for human nutrition (Dordrecht, Netherlands). doi:10.1007/s11130-025-01401-zPubMed 41076614DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error