E920
L-cysteine
What the research shows
No concerns
none of the findings here link it to harm
A building block of protein found in all living things.1
- May not be vegan
- May not be vegetarian
- EU permitted
What research says
Studies in people
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Benefit
Hangover symptoms2
In a study of men, L-cysteine seemed to prevent or ease hangover, nausea, headache, stress and anxiety.
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Benefit
Memory and brain aging3
In people, l-cysteine with vitamin D may help mild memory problems, but scientists do not yet know for sure.
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Benefit
DNA damage after exercise4
In basketball players, one month of l-cysteine may reduce DNA damage from training.
Animal and lab studies only
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Benefit
Blood sugar control5
In animal studies, L-cysteine improved how the body handles sugar, but scientists do not yet know whether it helps people with diabetes.
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Benefit
Vitamin D absorption6
In lab and animal studies, l-cysteine helped the body turn vitamin D into the form it uses.
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Benefit
Blood vessel health in diabetes7
L-cysteine reduced blood vessel cell stickiness caused by high sugar and ketones.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 184.1271
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Preservatives
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 2,256 products on Open Food Facts that list l-cysteine.
- TIGER ROLLS WITH SOURDOUGH JASON'S EVERY DAY · 320 g 4 additives
- Protein Thin Bagels Warburtons · 4x60 g 7 additives
- Soft Pittas Warburtons · 4 7 additives
- Wraps Roco Loco · 6 x 62 g 10 additives
- Soft White Farmhouse Warburtons · 800 g, 19 slices 5 additives
- White Tortilla Wraps TESCO · 8 Pack 7 additives
References
- 1Cysteine. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Eriksson CJP, Metsälä M, Möykkynen T, et al. L-Cysteine Containing Vitamin Supplement Which Prevents or Alleviates Alcohol-related Hangover Symptoms: Nausea, Headache, Stress and Anxiety. Alcohol Alcohol. 2020;55(6):660-666. doi:10.1093/alcalc/agaa082
- 3Jain SK, Stevens CM, Margret JJ, Levine SN. Alzheimer's Disease: A Review of Pathology, Current Treatments, and the Potential Therapeutic Effect of Decreasing Oxidative Stress by Combined Vitamin D and l-Cysteine Supplementation. Antioxid Redox Signal. 2024;40(10-12):663-678. doi:10.1089/ars.2023.0245
- 4Tsakiris S, Parthimos T, Parthimos N, Tsakiris T, Schulpis KH. The beneficial effect of L-cysteine supplementation on DNA oxidation induced by forced training. Pharmacol Res. 2006;53(4):386-90. doi:10.1016/j.phrs.2006.01.008
- 5Jain SK. L-cysteine supplementation as an adjuvant therapy for type-2 diabetes. Can J Physiol Pharmacol. 2012;90(8):1061-4. doi:10.1139/y2012-087
- 6Jain SK, Justin Margret J, Abrams SA, Levine SN, Bhusal K. The Impact of Vitamin D and L-Cysteine Co-Supplementation on Upregulating Glutathione and Vitamin D-Metabolizing Genes and in the Treatment of Circulating 25-Hydroxy Vitamin D Deficiency. Nutrients. 2024;16(13). doi:10.3390/nu16132004
- 7Kanikarla-Marie P, Jain SK. L-Cysteine supplementation reduces high-glucose and ketone-induced adhesion of monocytes to endothelial cells by inhibiting ROS. Mol Cell Biochem. 2014;391(1-2):251-6. doi:10.1007/s11010-014-2009-3